Growth Hormone Clinical Research
By Lisa Wells, RN
Human growth hormone (GH or HGH) is the first substance that has been clinically shown to reverse the effects of aging. The average life expectancy is expected to increase due to advances in medicine, and now that growth hormone supplementation is at the forefront of anti-aging research, the average life expectancy may soon be up to 130 years.1
Dr. Daniel Rudman's Ground Breaking HGH Clinical Study
In 1990 research studies done by Dr. Daniel Rudman, an endocrinologist from Madison, Wisconsin, shocked the scientific and medical communities.
The results of his studies were published in The New England Journal of Medicine Dr. Rudman's volunteers who participated in the studies had an average age of 71 years.
In Dr. Rudman's double-blind placebo study the patients who were taking HGH saw what appeared to be a reversal of the aging process of 10 to 20 years.
The patients in the study who did not receive growth hormone, but received a placebo, showed no age reversal, they continued to age normally.2
Human growth hormone is required in order for the body to heal and rejuvenate itself, it restores shrinking cells back to their normal size, however, it declines at a rate of about 14% per decade after the age of 21 to 30.
HGH Research of Dr. L. Cass Terry and Dr. Edmund Chein
A major study on the effects of growth hormone was done by Dr. Edmund Chein, director of the Palm Springs Life Extension, and his associate Dr. L. Cass Terry, of the Medical College of Wisconsin.
Dr. Chein follows a certain protocol that involves administering low dose, high frequency injections to patients with an IGF-1 level less than 350 mg/ml. He also restores the other hormones of his patients. He claims that his anti-aging program has been 100% effective for all of his patients. He guarantees his patients a 1.5 - 2.5% increase in bone density, a loss of 10% body fat, and an increase of 10% muscle mass with every six months of therapy. These improvements may continue until the patient reaches the body composition of a 20 year old.3
Dr. Terry collected data of 202 patients he has treated with HGH injection therapy at the Life Extension Institute between 1994 and 1996 and these were the results:
Strength, Exercise and Body Fat Improved
Muscle Strength - 88%
Muscle Size - 81%
Body Fat Loss - 72%
Exercise Tolerance - 81%
Exercise Endurance - 83%
Healing, Flexibility and Resistance Improved
Healing of old injuries - 55%
Healing of other injuries - 61%
Healing Capacity - 71%
Back Flexibility - 53%
Resist to Common Illness - 73%
Energy, Emotions and Memory Improved
Energy Level - 84%
Emotional Stability - 67%
Attitude Toward Life - 78%
Memory - 62%
Skin and Hair Improved
Skin Texture - 71%
Skin Thickness - 68%
Skin Elasticity - 71%
Wrinkle Disappearance - 51%
New Hair Growth - 38%
Sexual Function Improved
Sexual Potency/Frequency - 75%
Duration of Penile Erection - 62%
Frequency of Night Time Urination - 57%
Hot Flashes - 58%
Menstrual Cycle Regulate - 38%
These improvements were reported to occur within one to three months with a tendency to continue improving over six months.3
Other studies have established that when the body's own human growth hormone releasing patterns are more closely mimicked, the results become more profound and side effects are minimized.
Growth Hormone Deficiency is Age Related
The American Association of Clinical Endocrinology and the American College of Endocrinology have suggested that growth hormone deficiency is age-related, and is defined by symptoms which include fatigue, increased weight and abdominal obesity, a decrease in muscle mass, and an increase in fat, a decrease in physical strength, a decrease in restful sleep, an impairment of the sense of well being, a decrease in exercise capacity and physical performance, and reduced cardiac output.
Today, we have the results of additional clinical studies supporting the idea that restoring HGH in adults to a more healthy level can delay and even reverse many of the damaging effects of the aging process.
1. Klatz, Ronald, "Grow Young With HGH," HarperPerennial, 1997.
2. Rudman, Daniel, Feller, Axel G, et al, "Effects of Human Growth Hormone in Men over 60 Years Old," The New England Journal of Medicine, 1990; 323:1561-1563, DOI: 10.1056/NEJM199011293232212
3. Chein, Edmund, Voit, Daniel G, Terry, L Cass, "Clinical Experiences Using a Low-Dose, High-Frequency Human Growth Hormone Treatment Regimen," Journal of Advancement in Medicine, Volume 12, Number 3, Fall 1999.
4. Y. J. H. Janssen, M. Frolich, F. Roelfsema, A Low Starting Dose of Genotropin in Growth Hormone-Deficient Adults, The Journal of Clinical Endocrinology & Metabolism, Volume 82, Issue 1, 1 January 1997, Pages 129-135, https://doi.org/10.1210/jcem.82.1.3669