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Normal Hormone Levels
By Lisa Wells, RN
Below are listed the normal blood levels of IGF-1, testosterone, the estrogens, estradiol, estriol, estrone, progesterone, and DHEA.
Please note, all hormones decrease with age so most of the levels listed below are what modern Western medicine considers normal for age. This means they take into account the fact that without intervention the hormone levels in the body will continue to decline with age. Of course the decrease of these important hormones as we age plays a major role in the effects of aging.
Rather than focus on what is generally considered normal for age we in anti-aging and functional medicine focus more on the hormone levels that are required in order for the body of each individual patient to function optimally. Many times this means having a blood test level that is at the mid to high end of the normal ranges below.
IGF-1 Levels Used For Checking Growth Hormone
Once released by the pituitary gland human growth hormone remains in the bloodstream for only a few minutes before being taken in by the liver. For this reason measuring an accurate HGH blood level requires an involved and time consuming stimulation test that has certain risk factors.
Because IGF-1 (insulin-like growth factor #1) is released in response to HGH and remains stable in the bloodstream longer it is the test normally used for checking HGH in adults.
| IGF-1 Levels (Somatomedin C) | ||
| Age | Males - ng/ml | Females - ng/ml |
| 2 months - 5 years | 17 - 248 | 17 - 248 |
| 6 - 8 years | 88 - 474 | 88 - 474 |
| 9 - 11 years | 110 - 565 | 117 - 771 |
| 12 - 15 years | 202 - 957 | 261 - 1096 |
| 16 - 24 years | 182 - 780 | 182 - 780 |
| 25 - 39 years | 114 - 492 | 114 - 492 |
| 40 - 54 years | 90 - 360 | 90 - 360 |
| > 55 years | 71 - 290 | 71 - 290 |
| Testosterone (Total) | |||
| Males | ZRT Lab Reference Range | Males | Reference Range |
| Age | pg/ml | Age | ng/dL |
| All Ages | 44 - 148 | 20 - 30 | 280 - 1205 |
| 16 - 30 | 72 - 148 | 30 - 40 | 350 - 1010 |
| 31 - 50 | 58 - 120 | 40 - 50 | 255 - 1025 |
| 51 - 70 | 44 - 94 | 50 - 60 | 255 - 950 |
| > 70 | 30 - 77 | 60 - 70 | 120 - 870 |
| 70 - 80 | 38 - 850 | ||
| 80 - 90 | 28 - 390 | ||
| Females | |||
| Age | ng/dL | ||
| adults | 2 - 45 | ||
| Estradiol | |||
| Females | ZRT Lab Reference Range - pg/ml | ||
| Premenopausal | 1.3 - 3.3 | ||
| Postmenopausal | 0.5 - 1.7 | ||
| Males | ZRT Lab Reference Range - pg/ml | ||
| 0.5 - 2.2 | |||
| Females | Quest Diagnostics Reference Range - pg/ml | ||
| Untreated Postmenopausal | < 31 | ||
| Treated Postmenopausal | < 94 | ||
| Oral Contraceptives | < 103 | ||
| Ovulating, Follicular | < 161 | ||
| Ovulating, Follicular 2 to 3 days | < 85 | ||
| Ovulating, Peri-ovulatory +/- 3 days | < 34 - 400 | ||
| Ovulating, Luteal | 27 - 246 | ||
| Estriol | |
| Females | ZRT Lab Reference Range - pg/ml |
| Premenopausal | < 7 |
| Postmenopausal | < 7 |
| Males | |
| 0 - 3 | |
| Estrone | |
| Females | ZRT Lab Reference Range - pg/ml |
| 1.6 - 5 | |
| Males | |
| 0 - 3 | |
| Estrogens | |
| Females | Reference Range - pmol/l |
| Prepubertal | 12 - 57 |
| Follicular Phase | 29 - 525 |
| Luteal Phase | 126 - 478 |
| Postmenopausal | 23 - 103 |
| Males | |
| Prepubertal | 12 - 55 |
| Adult | 38 - 139 |
| Progesterone | |||
| Females | ZRT Lab Range - pg/ml | ng/ml | pmol/l |
| Luteal Phase | 75 - 270 | 4 - 20 | 11.6 - 58 |
| Follicular Phase | 12 - 100 | 0.3 - 0.8 | 0.9 - 2.3 |
| Postmenopausal | 12 - 100 | ||
| Males | |||
| 15 - 100 | 0.12 - 0.3 | 0.3 - 0.9 | |
| Quest Diagnostics | ng/ml | Quest Diagnostics | ng/ml |
| = or > 18 Years Old | Pregnancy | ||
| Follicular Phase | < 1.0 | 1st Trimester | 4.1 - 34.0 |
| Luteal Phase | 2.6 - 21.5 | 2nd Trimester | 24.0 - 76.0 |
| Postmenopausal | < 0.5 | 3rd Trimester | 52.0 - 302.0 |
Below you will see two tables of values for DHEA sulfate. The first shows the difference in what modern medicine considers normal for age and what functional and anti-aging medicine considers optimum for bodily function. The 2nd table shows a breakdown of what the U.S. NIH considers normal. Notice the wide range in the values of the NIH and the difference in the standard and optimum ranges.
| DHEA-S | |||
| Standard Range ug/dL | Optimum Range ug/dL | ||
| Males | 280 - 640 | 400 - 500 | |
| Females | 65 - 380 | 350 - 430 | |
| DHEA-S | ||
| National Institute of Health | ||
| Age | Males | Females |
| Standard Range ug/dL | Standard Range ug/dL | |
| 18 - 19 | 108 - 441 ug/dL | 145 - 395 ug/dL |
| 20 - 29 | 280 - 640 | 65 - 380 |
| 30 - 39 | 120 - 520 | 45 - 270 |
| 40 - 49 | 95 - 530 | 32 - 240 |
| 50 - 59 | 70 - 310 | 26 - 200 |
| 60 - 69 | 42 - 290 | 13 - 130 |
| 69 + | 28 - 175 | 17 - 90 |
Please note: The reference ranges at different labs may vary and may be different than the ranges posted here. Your own lab report should show the correct normal ranges for your specific tests. Please consult your private healthcare provider.
Important Information About the Hormones That Decrease With Age
Bibliography
Clemmons, David R, "Clinical Utility of Measurements of Insulin-Like Growth Factor 1," Nature Clinical Practice Endocrinology & Metabolism volume 2, August 2006, pages 436–446.Tillmann, V, Patel, L, Gill, MS, Whatmore, AJ, et al, "Monitoring Serum Insulin‐Like Growth Factor-1 (IGF-1), IGF Binding Protein-3 (IGFBP-3), IGF-1/IGFBP-3 Molar Ratio and Leptin During Growth Hormone Treatment For Disordered Growth," Clinical Endocrinology, September 2000, Vol 53, Issue 3, Pages 329-336.
Cutfield, WS, Lundgren, F, "Insulin-Like Growth Factor 1 and Growth Responses during the First Year of Growth Hormone Treatment in KIGS Patients with Idiopathic Growth Hormone Deficiency, Acquired Growth Hormone Deficiency, Turner Syndrome and Born Small for Gestational Age," Hormone Research in Pediatrics, 2009;71(suppl 1):39-45.
