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Normal Hormone Levels

By Lisa Wells, RN

Normal levels of hormones

Below are listed the normal blood levels of IGF-1, testosterone, the estrogens, estradiol, estriol, estrone, progesterone, and DHEA.

Please note, all hormones decrease with age so most of the levels listed below are what modern Western medicine considers normal for age. This means they take into account the fact that without intervention the hormone levels in the body will continue to decline with age. Of course the decrease of these important hormones as we age plays a major role in the effects of aging.

Rather than focus on what is generally considered normal for age we in anti-aging and functional medicine focus more on the hormone levels that are required in order for the body of each individual patient to function optimally. Many times this means having a blood test level that is at the mid to high end of the normal ranges below.

IGF-1 Levels Used For Checking Growth Hormone

Once released by the pituitary gland human growth hormone remains in the bloodstream for only a few minutes before being taken in by the liver. For this reason measuring an accurate HGH blood level requires an involved and time consuming stimulation test that has certain risk factors.

Because IGF-1 (insulin-like growth factor #1) is released in response to HGH and remains stable in the bloodstream longer it is the test normally used for checking HGH in adults.

IGF-1 Levels (Somatomedin C)
Age Males - ng/ml Females - ng/ml
2 months - 5 years 17 - 248 17 - 248
6 - 8 years 88 - 474 88 - 474
9 - 11 years 110 - 565 117 - 771
12 - 15 years 202 - 957 261 - 1096
16 - 24 years 182 - 780 182 - 780
25 - 39 years 114 - 492 114 - 492
40 - 54 years 90 - 360 90 - 360
> 55 years 71 - 290 71 - 290
Testosterone (Total)
Males ZRT Lab Reference Range Males Reference Range
Age pg/ml Age ng/dL
All Ages 44 - 148 20 - 30 280 - 1205
16 - 30 72 - 148 30 - 40 350 - 1010
31 - 50 58 - 120 40 - 50 255 - 1025
51 - 70 44 - 94 50 - 60 255 - 950
> 70 30 - 77 60 - 70 120 - 870
    70 - 80 38 - 850
    80 - 90 28 - 390
       
    Females  
    Age ng/dL
    adults 2 - 45

Testosterone

Estradiol
Females ZRT Lab Reference Range - pg/ml
Premenopausal 1.3 - 3.3
Postmenopausal 0.5 - 1.7
Males ZRT Lab Reference Range - pg/ml
  0.5 - 2.2
Females Quest Diagnostics Reference Range - pg/ml
Untreated Postmenopausal < 31
Treated Postmenopausal < 94
Oral Contraceptives < 103
Ovulating, Follicular < 161
Ovulating, Follicular 2 to 3 days < 85
Ovulating, Peri-ovulatory +/- 3 days < 34 - 400
Ovulating, Luteal 27 - 246
Estriol
Females ZRT Lab Reference Range - pg/ml
Premenopausal < 7
Postmenopausal < 7
Males  
  0 - 3
Estrone
Females ZRT Lab Reference Range - pg/ml
  1.6 - 5
Males  
  0 - 3
Estrogens
Females Reference Range - pmol/l
Prepubertal 12 - 57
Follicular Phase 29 - 525
Luteal Phase 126 - 478
Postmenopausal 23 - 103
Males  
Prepubertal 12 - 55
Adult 38 - 139

Estrogen & Progesterone

Progesterone
Females ZRT Lab Range - pg/ml ng/ml pmol/l
Luteal Phase 75 - 270 4 - 20 11.6 - 58
Follicular Phase 12 - 100 0.3 - 0.8 0.9 - 2.3
Postmenopausal 12 - 100    
Males      
  15 - 100 0.12 - 0.3 0.3 - 0.9
Quest Diagnostics ng/ml Quest Diagnostics ng/ml
= or > 18 Years Old   Pregnancy  
Follicular Phase < 1.0 1st Trimester 4.1 - 34.0
Luteal Phase 2.6 - 21.5 2nd Trimester 24.0 - 76.0
Postmenopausal < 0.5 3rd Trimester 52.0 - 302.0
       

Below you will see two tables of values for DHEA sulfate. The first shows the difference in what modern medicine considers normal for age and what functional and anti-aging medicine considers optimum for bodily function. The 2nd table shows a breakdown of what the U.S. NIH considers normal. Notice the wide range in the values of the NIH and the difference in the standard and optimum ranges.

DHEA-S
  Standard Range ug/dL Optimum Range ug/dL
Males 280 - 640 400 - 500
Females 65 - 380 350 - 430
DHEA-S
National Institute of Health
Age Males Females
  Standard Range ug/dL Standard Range ug/dL
18 - 19 108 - 441 ug/dL 145 - 395 ug/dL
20 - 29 280 - 640 65 - 380
30 - 39 120 - 520 45 - 270
40 - 49 95 - 530 32 - 240
50 - 59 70 - 310 26 - 200
60 - 69 42 - 290 13 - 130
69 + 28 - 175 17 - 90

Please note: The reference ranges at different labs may vary and may be different than the ranges posted here. Your own lab report should show the correct normal ranges for your specific tests. Please consult your private healthcare provider.

Important Information About the Hormones That Decrease With Age

Lisa Wells, RN

Bibliography

Clemmons, David R, "Clinical Utility of Measurements of Insulin-Like Growth Factor 1," Nature Clinical Practice Endocrinology & Metabolism volume 2, August 2006, pages 436–446.

Tillmann, V, Patel, L, Gill, MS, Whatmore, AJ, et al, "Monitoring Serum Insulin‐Like Growth Factor-1 (IGF-1), IGF Binding Protein-3 (IGFBP-3), IGF-1/IGFBP-3 Molar Ratio and Leptin During Growth Hormone Treatment For Disordered Growth," Clinical Endocrinology, September 2000, Vol 53, Issue 3, Pages 329-336.

Cutfield, WS, Lundgren, F, "Insulin-Like Growth Factor 1 and Growth Responses during the First Year of Growth Hormone Treatment in KIGS Patients with Idiopathic Growth Hormone Deficiency, Acquired Growth Hormone Deficiency, Turner Syndrome and Born Small for Gestational Age," Hormone Research in Pediatrics, 2009;71(suppl 1):39-45.

 

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