IGF-1- the Growth Factor of Youth

IGF-1 (Insulin-like Growth Factor-1), also known as Somatomedin C, is the most important growth factor that comes from human growth hormone (HGH).

The majority of benefits related to HGH are actually brought about as a result of IGF-1 and other growth factors such as IGF-2. HGH acts as the general and the growth factors are the soldiers who do the work at the cellular level.

The body is comprised of many systems that work together. Growth factors are small natural proteins that regulate cell growth and control the metabolic processes. They enable the cells in the hormonal, immune, and nervous systems to communicate and coordinate their growth, death, regeneration, and functioning. Cell reproduction slows down as we age; unless they are prompted by the growth factors they go into a resting phase.

IGF-1 is required for normal growth and health maintenance. It helps to transfer glucose through the cell membranes and helps to supply the raw materials that cells need for growth and repair. It also regulates cell growth by moving the cells from the resting phase to the active phase of its cycle and it increases the cell’s ability to complete DNA synthesis. Clinical evidence shows that low IGF-1 levels play a key role in the degenerative changes brought about with aging.

Because measuring a human growth hormone blood level is so involved and risky doctors often measure a blood IGF-1 level instead. Once in the bloodstream HGH is quickly taken in by the liver and converted into IGF-1.

Please note the normal IGF-1 ranges below are what traditional Western medicine considers normal for age. These normal ranges take into account the fact that without intervention the IGF-1 level of individuals with continue to decline with age.

We in anti-aging medicine believe that aging adults are better off having an IGF-1 level at the higher end of their normal range rather than at the lower end.

IGF-1 Levels Considered "Normal For Age"
Age	Male (ng/ml)	Female (ng/ml)
2 months - 5 years	17-248	17-248
6 - 8 years	88-474	88-474
9 - 11 years	110-565	117-771
12 - 15 years	202-957	261-1096
16 - 24 years	182-780	182-780
25 - 39 years	114-492	114-492
40 - 54 years	90-360	90-360
>55 years	71-290	71-290

More Potent Than Human Growth Hormone

IGF-1 (Somatomedin-C) is 10 times more potent than HGH (Somatotropin) and some researchers and clinicians believe that it can be more effective when used as a therapy than human growth hormone.

By taking IGF-1 directly the pituitary gland and liver are bypassed, which is good if they are damaged or worn out due to aging. Dr. Keith Kelly, Ph.D., who has done much research on anti-aging believes that the real future of anti-aging medicine lies with IGF-1.

Lisa Wells, RN

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